KMID : 0882420080740030310
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Korean Journal of Medicine 2008 Volume.74 No. 3 p.310 ~ p.314
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A case of pancreatic intraepithelial neoplasm (PanIN-III) manifesting as recurrent pancreatitis
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Sohn Byeong-Seok
Seo Dong-Wan Kim Song-Chael Lee Sung-Koo Lee Sang-Soo Jang Se-Jin Kim Myung-Hwan
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Abstract
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Acute recurrent pancreatitis has a variety of etiologies. We experienced a case of a tumor-forming pancreatitis in a 49 year old Korean woman who also had pancreatic intraepithelial neoplasm III (PanIN-III), and this manifested just like recurrent pancreatitis. She had a history of recurrent pancreatitis. She was found to have an early stage of pancreatic cancer via computed tomography and magnetic resonance cholangiopancreatography. EUS guided fine needle aspiration (FNA) showed only many acinar cells of the pancreas. But due to the possibility of her having pancreatic carcinoma, she underwent distal pancreatectomy and splenectomy with lymph node dissection. Pathologically, the tumor of the pancreatic body showed secondary changes with focal fibrosis from the localized chronic pancreatitis. PanIN-III was observed in the pancreatic duct within the tumor, and there were no cancerous findings in the 13 dissected lymph nodes. (Korean J Med 74:310-314, 2008)
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KEYWORD
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Chronic pancreatitis, Focal fibrosis, PanIN, Recurrent pancreatitis
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